Speakers at ICG-13

Speakers at ICG-13

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Biography

My experiences and interests are diverse. Born in California my family originated in Scandinavia. I am currently working at the Sooam Biotech Research Institute.  I have a background in organic agriculture, bachelors in biology, masters in applied biotechnology and thoroughly enjoy all aspects of the created world. I was born and raised outside of a small town in California, moved through the US during my bachelors, working summers and free time with work on and related to the family farm. After college I returned home and became even more involved with agriculture. I worked for several years before pursuing my masters, to try and satiate some of my curiosity for the natural world. During this time, I was able to do missions work in Nicaragua where I learned Spanish and developed a heart for the developing world. Having long desired to return to my ancestral home, combined with the fact that the universities are rated some of the highest in the world, I moved to Uppsala Sweden where I completed my masters in Applied Biotechnology. Afterwards I moved to Lund University to do my doctoral work in the department of Experimental Medical Science and the department of Laboratory Medicine, where I focused on work related to cancer and the extracellular matrix. Following my PhD, I transitioned to Seoul, South Korea to work with and develop techniques for the preservation and restoration of endangered and extinct species.

 
My love for nature, interest in business, and heart for humanity and the environment match well with and link my varied interest and expertise. I’m always looking for the next step and new idea and hope to be able to pursue the completion of some of the more key goals and projects to better humanity and the world through value creation in business, science and technology. In my spare time I enjoy the outdoors including hunting, fishing, mushroom picking and the like. I also involve myself in committees, sports and my local church whenever possible.

 

I strive to continue the pursuit of knowledge and the development of value in whatever I do. My current and future goals are related to preservation and restoration of endangered and extinct species, seeing cancer and diseases treated with increasing efficiency and the betterment of our world increasing species, environment and ultimately human wellbeing. I am optimistic about the future and look forward to seeing the advancements it will unveil. 


Abstract

Preservation and Restoration of Endangered and Extinct Species: A work in progress.

P. Olof Olsson Author Number

Author Number Sooam Biotech Research Foundation, 64 Gyunginro Guro-gu 08359 Seoul, South Korea.

Currently more species are endangered than have ever been before and largely due to direct and indirect human influence. A question often posed when discussing animal conservation, especially work on restoration of extinct species, is what the motivation. Why should we extend the effort to save and restore animal species or populations that have died out? Our answer depends in large part on our views about our role in the equation, the reason for extinction, the species itself and the effect on the ecosystem. Whether the intrinsic and extrinsic value of the species of question warrants the effort, basically should we do it and is it worth the cost? Once we agree to intervene the question becomes how. To answer this, we address the methods of population management, captive breeding and, discussed herein, assisted reproductive technologies.

Aside from conventional reproductive means for endangered species, including the often unsuccessful, in vitro fertilization (IVF). The approach using somatic cell nuclear transfer (SCNT) using similar species, which has not largely been pursued, is the. Our approach illustrates a number of the successes and difficulties using interspecies SCNT and embryo transfer. We are moving forward to include cell and molecular techniques to better efficiencies and enable the development of embryos to term. Although to date only bacteria have been produced solely by this method, new technologies, most notably including genome manipulation and synthesis, may make the potential for extinct species restoration more obtainable than previously imagined.

We have shown that SCNT is a viable method for the cloning of similarly related species. Preliminary success in restoration techniques has been achieved by us in related members of the canine family, wolves and coyotes, as well as by others in related bovid species, e.g, cattle and guar. Success has however been limited to the most closely related of species and is thought primarily to be due to maternal- fetal or genomic- mitochondrial incompatibilities. These failures have been equally instructive in the requirements for further attempts and the need for specific modifications and advancements to established technologies.

The presence of DNA and intact cells from extinct species is scare, however, samples do exist. We conclude that no single, but rather combined ART technologies are likely to be the most successful in recovery of these species. Preliminary conclusions are positive, illustrating the potential for further progress.  More work is required to expand current and introduce new technologies to this field. International regulatory roadblocks remain an obstacle for the transfer of material.

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